College Hoops

Iowa State vs. Pittsburgh prediction, odds: 2023 NCAA Tournament picks, March Madness best bets by top model

Iowa State vs. Pittsburgh prediction, odds: 2023 NCAA Tournament picks, March Madness best bets by top model


Teams that struggled down the stretch meet when the 11th-seeded Pittsburgh Panthers battle the sixth-seeded Iowa State Cyclones in a 2023 NCAA Tournament Midwest Region first-round matchup on Friday. The Panthers (23-11, 14-6 ACC), who defeated Mississippi State 60-59 in Tuesday’s First Four game, lost three of their last four games to end the regular season and conference tournament. The Cyclones (19-13, 9-9 Big 12), who are making their second consecutive tournament appearance, lost eight of their past 12 games. Pittsburgh is making its 27th NCAA Tournament appearance, while Iowa State is making its 22nd.

Tipoff from Greensboro Coliseum in Greensboro, N.C., is set for 3:10 p.m. ET. Pitt leads the all-time series 1-0. The Cyclones are 4.5-point favorites in the latest Pittsburgh vs. Iowa State odds from Caesars Sportsbook, while the over/under for total points scored is set at 131.5. Before locking in any Iowa State vs. Pittsburgh picks, be sure to see the college basketball predictions and March Madness betting advice from SportsLine’s proven computer model.ย 

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters the 2023 NCAA Tournament 79-53 on all-top ratedย college basketball picksย this season, returning nearly $1,300 for $100 players. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Iowa State vs. Pitt and just locked in its picks and NCAA Tournament 2023 predictions. You can visit SportsLine now to see the model’s picks. Here are the college basketball odds and betting lines for Pitt vs. Iowa State:

  • Pittsburgh vs. Iowa State spread: Iowa State -4.5
  • Pittsburgh vs. Iowa State over/under: 131.5 points
  • Pittsburgh vs. Iowa State money line: Pittsburgh +162, Iowa State -195
  • PITT: The Panthers are 4-1 against the spread in their last five Friday games
  • ISU: The Cyclones are 9-4 ATS in their last 13 neutral site games
  • Pittsburgh vs. Iowa State picks: See picks at SportsLine

Why Iowa State can cover

The Cyclones are powered by senior guard Jaren Holmes, who has reached double-figure scoring in each of the last four games. In last Friday’s Big 12 Conference Tournament semifinal loss to Kansas, Holmes scored 16 points, and added four rebounds, two assists and two steals. A day earlier in a quarterfinal win over Baylor, he scored 17 points, grabbed five rebounds and dished out five…

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